
Oral tablet, daily or as-needed
Valacyclovir
An antiviral for genital herpes and cold sores. Taken at the first sign of an outbreak it shortens and softens it, and taken daily as suppressive therapy it reduces how often outbreaks happen and lowers the risk of transmitting the virus to a partner.
From $30/mo
Includes clinician visits, lab panel, medication, and unlimited messaging.
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Daily suppressive valacyclovir reduces the risk of transmitting genital herpes to a partner by roughly half in controlled trials.
What is in it
Valacyclovir hydrochloride.
How to take it
- For an outbreak: start at the very first tingle or symptom.
- For suppression: take once daily, every day.
- Drink plenty of water while taking it.
- Finish the course your clinician prescribes.
Why clinicians prescribe it
Two ways to use it
Episodic at the first sign of an outbreak, or daily to prevent them.
Protects a partner
Daily suppressive dosing meaningfully lowers the chance of passing herpes on.
Works on cold sores too
The same antiviral treats oral herpes, not only genital.
Common questions
Daily suppression suits frequent outbreaks or anyone wanting to protect a partner. Episodic dosing suits occasional outbreaks. Your clinician will help you choose based on how often yours occur.
Important safety information
Tell your clinician about kidney problems, since the dose may need adjusting. Stay well hydrated. Uncommon side effects include headache and nausea. Seek care for confusion or a marked drop in urination.
This page is not medical advice. Only a licensed clinician who has reviewed your history can decide whether this treatment is appropriate for you. Tell your clinician about every medication and supplement you take.


